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我们介绍的各种神器多半是从这里来的,你知道吗?

来源: 时间:2017-11-01 17:13:30

发表医学论文,最直接的好处就是晋升职称,这也是很多人发表医学论文的原因。但其实,发表医学论文的好处远不止这个,它的作用是重大的。首先我们得了解,医学论文是专业性、探索性很强的论文,基本任务就是探索未知,具体讲就是提出问题、解决问题,也就是提出前人从未提出过的问题,解决前人没有解决的问题。

我们介绍的各种神器多半是从这里来的,你知道吗?

翻看下日历,这都1月24号啦,留给中国队的时间不多了!


幸好川普又让Pubmed活过来了(讲真,Pubmed也没死啊~);幸好,StarBase又可以用了;幸好核酸研究又放出了一大波的数据库。。。(doi: 10.1093/nar/gkx1235)。


快扒拉扒拉看看能不能从这些数据库里补足自己立项的论据!


2018年Nucleic Acids Research数据库特辑上发表的新数据库

Database URL Brief description
3DIV http://kobic.kr/3div 3D-genome Interaction Viewer and  database
AAgMarker http://bioinfo.wilmer.jhu.edu/AAgMarker/index.jsp Serum autoantigen biomarkers  from proteome microarrays
aBiofilm http://bioinfo.imtech.res.in/manojk/abiofilm/ Anti-biofilm compounds
ActiveDriverDB https://activedriverdb.org/ Genome variation mapped against  post-translational modifications
ADReCS-Target http://bioinf.xmu.edu.cn/ADReCS-Target Adverse Drug Reactions linked to  proteins, genes and genetic variants
AmyPro http://amypro.net Proteins with validated  amyloidogenic regions
anti-CRISPRdb http://cefg.uestc.edu.cn/anti-CRISPRdb/ anti-CRISPR proteins
AraGWAS  Catalog https://aragwas.1001genomes.org Arabidopsis Genome-Wide  Association Studies
ASpedia http://combio.snu.ac.kr/aspedia Alternative Splicing Encylopedia
ChannelsDB http://ncbr.muni.cz/ChannelsDB Channels, pores and tunnels  found in biomacromolecular structures
CirGRDB http://cirgrdb.biols.ac.cn Regulation of RNAs in circadian  rhythms
ClusterCAD https://clustercad.jbei.org and  http://clustercad.igb.uci.edu Engineering of type I modular  polyketide synthases
CR2Cancer http://cis.hku.hk/CR2Cancer Chromatin Regulators and Cancer
CSCD http://gb.whu.edu.cn/CSCD Cancer-Specific cRNA Database
dbCAN-seq http://cys.bios.niu.edu/dbCAN Genome scale CAZymes and CAZyme  gene clusters
dbCoRC http://dbcorc.cam-su.org/ Core transcriptional Regulatory  Circuit models
DifferentialNET http://netbio.bgu.ac.il/diffnet Differential protein-protein  interactions in human tissues
DiseaseEnhancer http://biocc.hrbmu.edu.cn/DiseaseEnhancer/ Enhancer-disease associations
DISNOR http://disnor.uniroma2.it/ Protein interaction networks  linking disease genes
DreamBASE http://rna.sysu.edu.cn/dreamBase Human expressed pseudogenes: DNA Modification, RNA Regulation and bound proteins
ECOdrug http://www.ecodrug.org Evolutionary COnservation of  Drug targets
EpiDenovo http://61.148.58.210:8080/EpiDenovo/ The epigenome in mammalian  embryonic development
EPD https://peptracker.com/epd/ Encyclopedia of Protein Dynamics
EVLncRNAs http://biophy.dzu.edu.cn/EVLncRNAs/ Experimentally Validated lncRNAs  including disease indications
eRAM http://www.unimd.org/eram/ Annotated rare diseases
ExoRBase http://www.exoRBase.org Human blood exosome RNAs
FlavorDB http://cosylab.iiitd.edu.in/flavordb Flavour molecules
FusionDB http://services.bromberglab.org/fusiondb/ Functional-repertoire  similarity-based organism network
GVM http://bigd.big.ac.cn/gvm/ Genome Variation Map
HCMDB http://hcmdb.i-sanger.com/index Human Cancer Metastasis DataBase
HEDD http://zdzlab.einstein.yu.edu/1/hedd.php Human Enhancer Disease Database
ICG http://icg.big.ac.cn Internal Control Genes for  RT-qPCR normalization
IMOTA https://ccb-web.cs.uni-saarland.de/imota/ Interactive Multi-Omics-Tissue  Atlas
iPTMnet http://research.bioinformatics.udel.edu/iptmnet/ Post-Translational Modification  networks
ITSoneDB http://itsonedb.cloud.ba.infn.it/ Eukaryotic ribosomal RNA  Internal Transcribed Spacer 1  sequences
jMorp https://jmorp.megabank.tohoku.ac.jp/ Metabolomics and proteomics of  1000 healthy Japanese people
LINCS  Data Portal http://lincsportal.ccs.miami.edu/dcic-portal/ Cell-based perturbation-response  signatures
LinkedOmics http://www.linkedomics.org Multi-omics analysis of 32  cancers
Lnc2Meth http://www.bio-bigdata.com/Lnc2Meth lncRNAs and DNA methylation
m6AVar http://m6avar.renlab.org/ Human variants affecting m6A  sites
MeDReaders http://medreader.org/ Transcription factors binding  methylated DNA
microbiomeDB http://microbiomeDB.org Mining and analysing microbiome  data
MINTbase https://cm.jefferson.edu/MINTbase/ Mitochondrial and nuclear tRNA  fragments
miRCarta https://mircarta.cs.uni-saarland.de/ miRNAs and precursors
mirTrans http://mcube.nju.edu.cn/jwang/lab/soft/mirtrans/ Cell-specific transcriptional  information for human miRNAs
MIST http://fgrtools.hms.harvard.edu/ProteinSearch/ Model organism molecular  interaction data
MGA http://ccg.vital-it.ch/mga/ Mass Genome Annotation
MMP https://mmp.sfb.uit.no/databases/ Marine Metagenomics Portal
MSDD http://www.bio-bigdata.com/msdd/ miRNA SNP Disease Database
mSignatureDB http://tardis.cgu.edu.tw/msignaturedb Mutational signatures in human  cancers
MVP http://mvp.medgenius.info Microbe-phage interactions
NPASS http://bidd2.nus.edu.sg/NPASS/ Natural Product quantitative  Activities
OverGeneDB http://overgenedb.amu.edu.pl Overlapping protein-coding genes
PAMDB http://pseudomonas.umaryland.edu Pseudomonas aeruginosa  Metabolome DataBase
PancanQTL http://bioinfo.life.hust.edu.cn/PancanQTL/ Expression quantitative loci  (eQTL) analysis of cancer samples
PedAM http://www.unimd.org/pedam/ Pediatric Disease Annotation  & Medicine
PCSD http://systemsbiology.cau.edu.cn/chromstates Plant Chromatin State Database
PGG.Population https://www.pggpopulation.org Genomic diversity of diverse  human populations
PharmacoDB http://pharmacodb.pmgenomics.ca Pharmacogenomics of cancer cell  lines
PICKLES http://pickles.hart-lab.org Pooled In-vitro Crispr Knockout  Library Essentiality Screens
PIT-DB http://pitdb.org Proteomics Informed by  Transcriptomics
Planteome http://www.planteome.org Portal for plant ontologies and  annotations
PopHuman http://pophuman.uab.cat Population genomics-oriented  genome browser
qPrimerDB http://biodb.swu.edu.cn/qprimerdb qPCR primers for 200 organisms
RISE http://rise.zhanglab.net RNA-RNA interactions
RNArchitecture http://iimcb.genesilico.pl/RNArchitecture/ Structural classification of  RNAs
SBCCDB http://sbcddb.moffitt.org Sleeping Beauty Cancer Driver  DataBase
SCPortalen http://single-cell.clst.riken.jp/ Human and mouse single-cell  centric database
SEECancer http://biocc.hrbmu.edu.cn/SEECancer Evolutionary-stage specific  somatic events in cancer
StemMapper http://stemmapper.sysbiolab.eu Stem cell gene expression
STCRDab http://opig.stats.ox.ac.uk/webapps/stcrdab Structural T-Cell Receptor  Database
SysteMHC  Atlas https://systemhcatlas.org/ Immunopeptidomics of MHC-bound  peptides
Tabloid  Proteome http://iomics.ugent.be/tabloidproteome Protein associations inferred  from Mass Spectrometry
Target-Pathogen http://target.sbg.qb.fcen.uba.ar/patho Drug target optimisation in  pathogens
TC3A http://tc3a.org/ 3’ untranslated regions,  alternative polyadenylation and cancer
TissGDB http://zhaobioinfo.org/TissGDB Tissue-specific Gene DataBase in  cancer
TranslatomeDB http://www.translatomedb.net/ Translatome data from RNC-Seq  and Ribo-Seq
TriForC  database http://bioinformatics.psb.ugent.be/triforc/ Triterpene pathways
TCSBN http://inetmodels.com Tissue and Cancer-Specific  Biological Networks
VarCards http://varcards.biols.ac.cn/ Interpretation of coding  variants in the human genome
VDJdb https://vdjdb.cdr3.net/. T-cell receptor sequences with  known antigen specificity
Virus  Taxonomy http://ictv.global Taxonomy of viruses

2018年Nucleic Acids Research更新了的老数据库

Database URL Brief description
BioMuta  and BioExpress https://hive.biochemistry.gwu.edu/biomuta  and https://hive.biochemistry.gwu.edu/bioxpress Cancer SNVs and gene expression
BioStudies https://www.ebi.ac.uk/biostudies/ Data of all kinds relating to a  single study
iSyTE http://research.bioinformatics.udel.edu/iSyTE integrated Systems Tool for Eye  gene discovery
miRandola http://mirandola.iit.cnr.it/ Extracellular and circulating  non-coding RNAs
mirDIP http://ophid.utoronto.ca/mirDIP/ microRNA Data Integration Portal
MNDR http://www.rna-society.org/mndr/ Mammal ncRNA-Disease Repository
NLSdb https://rostlab.org/services/nlsdb/ Nuclear Localization Signals
PAGER  2.0 http://discovery.informatics.uab.edu/PAGER/ Pathway, Annotated-list, and  Gene-signature Electronic  Repositor
ProteomicsDB https://www.ProteomicsDB.org Mass spectrometry of the human  proteome
PULDB http://www.cazy.org/PULDB new/ Polysaccharide Utilization Loci  in Bacteroidetes species
ReMap http://remap.cisreg.eu Transcription factor ChIP-seq  data
RMDB http://rmdb.stanford.edu Structure mapping of RNA
SuperDrug2 http://cheminfo.charite.de/superdrug2 Approved drugs
TRRUST  v2 http://www.grnpedia.org/trrust/ Transcriptional regulatory  interactions in human and mouse
TumorFusions http://www.tumorfusions.org Tumour fusion genes


 2018-01-24 机智的怪阿姨